Compile Data Set for Download or QSAR
Found 52 of ic50 data for polymerid = 50001170
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50246599(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50241252(2-[hydroxycarbamoylmethyl-(4-phenoxy-benzenesulfon...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50273426(CHEMBL515980 | N-(4-Phenoxybenzenesulfonyl)-N-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50066658((R)-N-(1-(hydroxyamino)-2-methylpropyl)-4-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137282(6-Hydroxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137287(2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50361601(CHEMBL1939846)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137281(2-Benzenesulfonyl-6-hydroxy-7-methoxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50294132(CHEMBL561963 | N-hydroxy-2-(N-isopropoxy-4'-isopro...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137285(6-(benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299053(CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299052(CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299056((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50241253(2-[(biphenyl-4-sulfonyl)-hydroxycarbamoylmethyl-am...)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299054(2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299058((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299055(CHEMBL573936 | [2-(4'-Methoxy-biphenyl-4-sulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 996nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299059(CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299065(CHEMBL575896 | N-Hydroxy-2-(4-phenoxy-benzenesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP53QNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299061(CHEMBL573935 | [2-(Biphenyl-4-sulfonyl)phenyl]acet...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50137280(6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50294131((R)-2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299063(CHEMBL584122 | N-Hydroxy-2-[4-(4-methoxy-phenoxy)b...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299067((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]propionic A...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299062(CHEMBL579067 | {2-[4-(4-Methoxy-phenoxy)benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP16 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3N0FPubMedDrugBank
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8DXNPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299057((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior Técnico

Curated by ChEMBL
LigandPNGBDBM50180601(3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed
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